一种药物组合物，所述药物组合物包含由至少一种稳定剂稳定的无定形碳酸钙(ACC)，用于在治疗选自肌营养不良症和轴突缺陷的疾病或状况中使用。提供了用于多种神经、肌肉和不育疾病和状况的治疗的稳定的无定形碳酸钙(ACC)。特别地，稳定的ACC可以用于在轴突缺陷和肌营养不良症的治疗中使用。此外，提供了在辅助生殖技术中使用的改进的方法。这样的方法的实例是体外受精和精子质量的改进。改进的IVF方法，例如，包括向受精和胚胎发育阶段发生在其中的细胞培养基添加稳定的ACC。

A pharmaceutical composition comprising amorphous calcium carbonate (ACC) stabilized by at least one stabilizer for use in the treatment of diseases or conditions selected from muscular dystrophy and axon defects. Provides stable amorphous calcium carbonate (ACC) for the treatment of a variety of neurological, muscular, and infertility diseases and conditions. In particular, stable ACC can be used in the treatment of axonal defects and muscular dystrophy. In addition, improved methods for use in assisted reproductive technologies are provided. Examples of such methods are in vitro fertilization and the improvement of sperm quality. Improved IVF methods, for example, include the addition of stable ACC to the cell culture medium in which the stages of fertilization and embryonic development occur.